When considering the best niches for an online store, it's important to focus on areas with high demand, low competition, and the potential for profitability. Here are some examples of lucrative niches:

1. Health and Wellness: With the increasing interest in personal health and well-being, this niche offers various opportunities. For instance, selling organic skincare products, fitness equipment, or specialized dietary supplements can be profitable. According to Grand View Research, the global organic personal care market is expected to reach $25.1 billion by 2025.

2. Sustainable Products: As consumers become more environmentally conscious, selling sustainable and eco-friendly products can be a successful niche. This could include items like reusable household products, zero-waste toiletries, or ethically sourced clothing. The global sustainable packaging market is predicted to reach $440.3 billion by 2027, as reported by Allied Market Research.

3. Pet Supplies: The pet industry continues to grow rapidly, making it a promising niche. Offering specialized pet products, such as organic pet food, unique toys, or personalized accessories, can attract a loyal customer base. The American Pet Products Association estimates that pet industry expenditures will exceed $100 billion in 2020.

4. Home Decor: Home decor is a consistently popular niche, with consumers constantly seeking new ways to improve their living spaces. Focusing on specific themes like minimalist decor, bohemian style, or vintage-inspired items can help differentiate your online store. According to Statista, the global home decor market is projected to reach $838 billion by 2027.

5. Subscription Boxes: Subscription boxes have gained significant popularity in recent years, offering a recurring revenue model. These boxes can be tailored to various interests, such as beauty, fitness, or gourmet food. The subscription box market is estimated to reach $16.3 billion by 2027, as reported by Grand View Research.

Remember, thorough market research is crucial when selecting a niche. Analyze trends, competition, and customer preferences to ensure your chosen niche aligns with your target audience's needs and desires.